Correlation between Perioperative Serum Albumin Levels and Complications in Usage of Drugs and Alcohol on Major Abdominal Surgery
Author(s): Mirton*, M. Iqbal Rival, Erkadius and Hesty Rhauda Ashan
Abstract
Background and purpose: Surgical trauma often leads to capillary leaks and inflammatory responses, which in turn cause a decrease in albumin levels. Hypoalbuminemia in patients undergoing major abdominal surgery can prolong treatment, increase the risk of complications, and elevate mortality rates. This study aims to explore the correlation between perioperative serum albumin levels and the occurrence of complications in major abdominal surgeries, particularly in the context of drug and alcohol usage.
Methods: This study is a prospective analytic research conducted with a cohort design at the Surgery Division of Dr. M Djamil Padang. The sample included 36 patients undergoing elective gastrointestinal surgery who met the inclusion criteria. Perioperative albumin levels were measured, and the data were analyzed using the chi-square method, with a significance threshold set at P ≤ 0.05.
Results: A significant correlation was found between postoperative albumin levels, postoperative albumin depletion, and the incidence of major postoperative complications in abdominal surgery.
Conclusion: Perioperative serum albumin levels can serve as an independent indicator of successful outcomes in major abdominal surgeries, especially in patients with a history of drug and alcohol usage.
