Formulation and Evaluation of Herbal Lozenges using Embelia ribes
Author(s): Sai Datri*, Lakshmana Rao, Mahesh Chandra Narayana, Durga Bhavani, Bhargavi, Yamini Padma Bhavani and Meghana
Abstract
Embelin hard candy lozenges were formulated to provide a slow release of the medicament for the treatment of bronchitis. It helps to make breathing easier by means of relaxing and opening air passage in the lungs. The local acting mechanism of embelin makes it more suitable to formulate as lozenges. This research is to develop a new dosage form of embelininto hard candy lozenges and their pharmaceutical standardization. The extraction of embelin from Embelia ribes, formulation of lozenges, processing procedure with extract-based herbal formulation, andexpansion for analytical standardization including qualitative and quantitative determinations were carried out. The formulation of hard candy lozenges was subjected to physico-chemical as well as in vitro drug release. Among all the formulations of hard candy lozenges F10 had shown in vitro drug release of 100.6% at the end of 30 minutes.