Lavanya Gunasekaran
Department of Microbiology, Rathnavel Subramaniam (RVS) College of Arts and Science, IndiaPublications
-
Research Article
In Vivo Schizonticidal Activity of Tribal Folklore Herbs of Western Ghats, Coimbatore, Tamil Nadu
Author(s): Dhanabalan Rangasamy*, Dhiviya Jeyarajan and Lavanya Gunasekaran
Background: Folklore medicinal plants Solanum trilobatum, Spathodea campanulata, Syzygium jambos and Tylophora indica fractions were examined for their antiplasmodial property in rodent malaria parasite Plasmodium berghei infected Swiss albino mice model. Method: Three in vivo assays (Peter’s four-day test, Rane’s curative and Prophylactic assay) were used in the study to determine the efficacy of plant extracts against Plasmodium berghei infection in the rodent model. Results: Peter’s four-day test showed significant parasite suppression of 97.72% (p?0.001) in Chloroquine (CQ) control group prolonging the mean survival time of animals for 32 days. Furthermore, effective parasite control (p<0.01) of 72.72% and 63.63% has been notice.. Read More»
DOI: 10.4303/JDAR/236227