Lourdes de Fatima Ibanez Valdes

Department of Family Medicine, Walter Sisulu University (WSU), South Africa

Publications

• Review Article   
  Impact of Gut Dysbiosis on Neuromyelitis Optica Spectrum Disorder: Implications for Alcohol and Substance Use
  Author(s): Lourdes de Fatima Ibanez Valdes and Foyaca-Sibat Humberto*
  
  The Central Nervous System (CNS) is affected by the chronic inflammatory autoimmune disease known as Neuromyelitis Optica Spectrum Disorder (NMOSD). Acute myelitis, area postrema syndrome, acute brainstem syndrome, Optic Neuritis (ON), and symptomatic cerebral syndrome are among the primary clinical symptoms of NMOSD. People with NMOSD may experience significant visual impairments, mobility difficulties, and even death. With a 9:1 female to male ratio, the prevalence of NMOSD varies from 0.5 to 4 afflicted per 100,000. NMOSD causes Astrocyte (As) and Oligodendrocyte (OLG) damage leading to demyelination and neurodegeneration. It typically does affect the optic nerves and the spinal cord, especially in long segments, but other features are helpful for the diagnosis. We review the relationship between NMOSD and dysbiosis as a main aid of this review. Implic.. Read More»
  DOI: 10.4303/JDAR/236418

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