Ramu Samineni
Department of Pharmaceutics, School of Pharmacy, Sandip University, Nashik, Maharastra, IndiaPublications
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Research Article
Hepatoprotective, Antioxidant And Anti- Inflammatory Potential Of Lentinula Edodes Extract Against Diclofenac-Induced Hepatic Damage In Wistar Rats
Author(s): G. Sravan Kumar Reddy*, B.V.V. Ravi Kumar, M. Surya Prabha, Uppara Venkatesh, Ramu Samineni and G. Mary Ratna Anitha
Lentinula edodes has traditionally been used to treat ulcers, bed sores, scalds and burns, hepatitis, gastritis, cancer, fungal infections, bronchial inflammation, and diabetes in Indian medicine, but its efficacy is unknown. Folklore, on the other hand, has given us numerous effective plant-based therapies. As a result, there are claims that Lentinula edodes (Omphalotaceae family) can be used to treat inflammation and hepatitis. The current study examined at the hepatoprotective, antioxidant, and anti-inflammatory properties of an alcoholic extract of Lentinula edodes. These fungi were able to inhibit the production of free radicals caused by the metabolism of the toxic substance diclofenac sodium. It also decreased diclofenac sodium-induced increases in Serum Aspartate Amino Transferase (AST), Alanine Amino Transferase (ALT), Alkaline Phosphatase (ALP), an.. Read More»
DOI: 10.4303/JDAR/236248