Santosh Kumar Ranajith
Department of Pharmacology, Centurion University of Technology and Management, IndiaPublications
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Research Article
Lobaria pulmonaria (L.) Hoffm. Attenuates Alcoholic Liver Injury in Wistar Rats by Reducing Oxidative Stress
Author(s): Kishore Naidu Killari*, Ho Viet Hieu, Prasad Konduri, Manasa Rampathoti, Santosh Kumar Ranajith and Mallikarjuna Rao Talluri
Background: Lichen, Lobaria pulmonaria (L.) Hoffm. belong to the family Lobariaceae. L. pulmonaria is being traditionally used to cure lung ailments, liver diseases, diarrhoea, heavy menstrual flow, and jaundice. With such a wide range of medicinal applications, it’s essential to scientifically authenticate traditional usage of L. pulmonaria. The present study is aimed to evaluate the antioxidant and hepatoprotective properties of selected ethanolic fractions of L. pulmonaria in alcohol induced oxidative stress in rats. Methods: In vitro antioxidant activities were performed using DPPH radical scavenging and ferric ions reducing power assays. In vivo hepatoprotective activity was assessed by using ethanol induced oxidative stress in Wistar rats. .. Read More»
DOI: 10.4303/jdar/236181