Sushma Chandrapalka

Research Scholar, Department of Pharmacy, GITAM School of Pharmacy, GITAM (Deemed to be University), India

Publications

• Research Article   
  Formulation and Optimization of Transferosomal Gel of Fusdic acid using Central Composite Design
  Author(s): Sushma Chandrapalka* and Annammadevi G. S
  
  Introduction: Impetigo can be treated by using Fusicidic Acid (FA), in the present study transferosomes of FA were prepared and incorporated into gel and studied for drug release, extent of permeability into the skin.   Methods: In the process of preparation of transferosomes various lipids, edge activators with various conditions were tested and found that it had good solubility in Dimyristolyphosphatidylcholine and Tween 80. Rotary thin film hydration method was selected as a method of choice for preparation of Transferosomes. Various ranges of lipid: surfactant, stirring speed, %entrapment efficiency, %drug content, zeta potential, drug release etc parameters were studied for prepared transferosomes. Results: Central composite design was used for optimizing the best formulation. Extrud.. Read More»
  DOI: 10.4303/JDAR/236296

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